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1

MMP-Responsive ‘Smart’ Drug Delivery and Tumor Targeting

Yao, Qing, Kou, Longfa, Tu, Ying, Zhu, Lin

Journal:

Trends in Pharmacological Sciences

Year:

2018

Language:

english

File:

PDF, 5.38 MB

english, 2018

2

OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro , in situ , and in vivo

Kou, Longfa, Sun, Rui, Xiao, Shuyi, Cui, Xiao, Sun, Jin, Ganapathy, Vadivel, Yao, Qing, Chen, Ruijie

Journal:

Year:

2020

Language:

english

File:

PDF, 2.69 MB

english, 2020

3

Interspecies prediction of oral pharmacokinetics of different lacidipine formulations from dogs to human: physiologically based pharmacokinetic modelling combined with biorelevant dissolution

Wu, Chunnuan, Kou, Longfa, Ma, Panqin, Gao, Lifang, Li, Bo, Li, Ran, Luo, Cong, Shentu, Jianzhong, He, Zhonggui, Sun, Jin

Journal:

Year:

2015

Language:

english

File:

PDF, 986 KB

english, 2015

4

Recent advances in drug delivery via the organic cation/carnitine transporter 2 (OCTN2/SLC22A5)

Kou, Longfa, Sun, Rui, Ganapathy, Vadivel, Yao, Qing, Chen, Ruijie

Journal:

Expert Opinion on Therapeutic Targets

Year:

2018

Language:

english

File:

PDF, 2.06 MB

english, 2018

5

Pharmacological actions and therapeutic potentials of bilirubin in islet transplantation for the treatment of diabetes

Yao, Qing, Jiang, Xue, Kou, Longfa, Samuriwo, Adelaide T, Xu, He-Lin, Zhao, Ying-Zheng

Journal:

Pharmacological Research

Year:

2019

Language:

english

File:

PDF, 1.35 MB

english, 2019

6

Biomaterial-engineered intra-articular drug delivery systems for osteoarthritis therapy

Kou, Longfa, Xiao, Shuyi, Sun, Rui, Bao, Shihui, Yao, Qing, Chen, Ruijie

Journal:

Year:

2019

Language:

english

File:

PDF, 2.08 MB

english, 2019

7

Endocytosis of ATB 0,+ (SLC6A14)-targeted liposomes for drug delivery and its therapeutic application for pancreatic cancer

Kou, Longfa, Huang, Huirong, Lin, Xinlu, Jiang, Xinyu, Bao, Shihui, Luo, Qiuhua, Sun, Jin, Yao, Qing, Ganapathy, Vadivel, Chen, Ruijie

Journal:

Expert Opinion on Drug Delivery

Year:

2020

Language:

english

File:

PDF, 3.79 MB

english, 2020

8

Aloe/poloxamer hydrogel as an injectable Î²-estradiol delivery scaffold with multi-therapeutic effects to promote endometrial regeneration for intrauterine adhesion treatment

Yao, Qing, Zheng, Ya-Wen, Lan, Qing-Hua, Wang, Li-Fen, Huang, Zhi-Wei, Chen, Rui, Yang, Yang, Xu, He-Lin, Kou, Longfa, Zhao, Ying-Zheng

Journal:

European Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 6.61 MB

2020

9

Relationship between dissolution and bioavailability for nimodipine colloidal dispersions: The critical size in improving bioavailability

Qiang Fu, Longfa Kou, Cheng Gong, Mo Li, Jin Sun, Dong Zhang, Meina Liu, Xiaofan Sui, Kai Liu, Siling Wang, Zhonggui He

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 904 KB

english, 2012

10

Enhanced Oral Delivery of Paclitaxel Using Acetylcysteine Functionalized Chitosan-Vitamin E Succinate Nanomicelles Based on a Mucus Bioadhesion and Penetration Mechanism

Lian, He, Zhang, Tianhong, Sun, Jin, Liu, Xiaohong, Ren, Guolian, Kou, Longfa, Zhang, Youxi, Han, Xiaopeng, Ding, Wenya, Ai, Xiaoyu, Wu, Chunnuan, Li, Lin, Wang, Yongjun, Sun, Yinghua, Wang, Siling, H

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 4.13 MB

english, 2013

11

Improved oral bioavailability of core–shell structured beads by redispersion of the shell-forming nanoparticles: Preparation, characterization and in vivo studies

Yao, Qing, Tao, Xiaoguang, Tian, Bin, Tang, Yilin, Shao, Yanjie, Kou, Longfa, Gou, Jingxin, Li, Xuechao, Yin, Tian, Tang, Xing

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2014

Language:

english

File:

PDF, 2.37 MB

english, 2014

12

The endocytosis and intracellular fate of nanomedicines: Implication for rational design

Kou, Longfa, Sun, Jin, Zhai, Yinglei, He, Zhonggui

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

13

Enteric Polymer Based on pH-Responsive Aliphatic Polycarbonate Functionalized with Vitamin E To Facilitate Oral Delivery of Tacrolimus

Wang, Menglin, Sun, Jin, Zhai, Yinglei, Lian, He, Luo, Cong, Li, Lin, Du, Yuqian, Zhang, Dong, Ding, Wenya, Qiu, Shuhong, Liu, Yuhai, Kou, Longfa, Han, Xiangfei, Xiang, Rongwu, Wang, Yongjun, He, Zhon

Journal:

Biomacromolecules

Year:

2015

Language:

english

File:

PDF, 8.70 MB

english, 2015

14

Withdrawn: OCTN2-mediated active targeting L-carnitine modified PLGA based nanoparticles for enhanced oral paclitaxel delivery

Sun, Jin, Kou, Longfa, Yao, Qing, He, Zhonggui

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 407 KB

english, 2015

15

Transporter occluded-state conformation-induced endocytosis: Amino acid transporter ATB0,+-mediated tumor targeting of liposomes for docetaxel delivery for hepatocarcinoma therapy

Luo, Qiuhua, Gong, Ping, Sun, Mengchi, Kou, Longfa, Ganapathy, Vadivel, Jing, Yongkui, He, Zhonggui, Sun, Jin

Journal:

Journal of Controlled Release

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

16

ATB 0,+ transporter-mediated targeting delivery to human lung cancer cells via aspartate-modified docetaxel-loading stealth liposomes

Luo, Qiuhua, Yang, Bin, Tao, Wenhui, Li, Jia, Kou, Longfa, Lian, He, Che, Xin, He, Zhonggui, Sun, Jin

Journal:

Biomaterials Science

Year:

2017

Language:

english

File:

PDF, 6.43 MB

english, 2017

17

Development and validation of a UPLC-MS/MS assay for the determination of gemcitabine and its L-carnitine ester derivative in rat plasma and its application in oral pharmacokinetics

Wang, Gang, Zhao, Dongyang, Chen, Hongxiang, Ding, Dawei, Kou, Longfa, Kan, Qiming, Liu, Xiaohong, He, Zhonggui, Sun, Jin

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

18

Combination of l -Carnitine with Lipophilic Linkage-Donating Gemcitabine Derivatives as Intestinal Novel Organic Cation Transporter 2-Targeting Oral Prodrugs

Wang, Gang, Chen, Hongxiang, Zhao, Dongyang, Ding, Dawei, Sun, Mengchi, Kou, Longfa, Luo, Cong, Zhang, Dong, Yi, Xiulin, Dong, Jinhua, Wang, Jian, Liu, Xiaohong, He, Zhonggui, Sun, Jin

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.39 MB

english, 2017

19

Cotransporting Ion is a Trigger for Cellular Endocytosis of Transporter-Targeting Nanoparticles: A Case Study of High-Efficiency SLC22A5 (OCTN2)-Mediated Carnitine-Conjugated Nanoparticles for Oral Delivery of Therapeutic Drugs

Kou, Longfa, Yao, Qing, Sun, Mengchi, Wu, Chunnuan, Wang, Jia, Luo, Qiuhua, Wang, Gang, Du, Yuqian, Fu, Qiang, Wang, Jian, He, Zhonggui, Ganapathy, Vadivel, Sun, Jin

Journal:

Advanced Healthcare Materials

Year:

2017

Language:

english

File:

PDF, 3.78 MB

english, 2017

20

Dual targeting of l -carnitine-conjugated nanoparticles to OCTN2 and ATB 0,+ to deliver chemotherapeutic agents for colon cancer therapy

Kou, Longfa, Yao, Qing, Sivaprakasam, Sathish, Luo, Qiuhua, Sun, Yinghua, Fu, Qiang, He, Zhonggui, Sun, Jin, Ganapathy, Vadivel

Journal:

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

21

L -Carnitine-conjugated nanoparticles to promote permeation across blood–brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2

Kou, Longfa, Hou, Yanxian, Yao, Qing, Guo, Weiling, Wang, Gang, Wang, Menglin, Fu, Qiang, He, Zhonggui, Ganapathy, Vadivel, Sun, Jin

Journal:

Artificial Cells, Nanomedicine, and Biotechnology

Year:

2017

Language:

english

File:

PDF, 2.42 MB

english, 2017

22

Ascorbate-conjugated nanoparticles for promoted oral delivery of therapeutic drugs via sodium-dependent vitamin C transporter 1 (SVCT1)

Luo, Qiuhua, Jiang, Mingyan, Kou, Longfa, Zhang, Ling, Li, Guyue, Yao, Qing, Shang, Lei, Chen, Ying

Journal:

Artificial Cells, Nanomedicine, and Biotechnology

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

23

Striking a Balance between Carbonate/Carbamate Linkage Bond- and Reduction-Sensitive Disulfide Bond-Bearing Linker for Tailored Controlled Release: In Situ Covalent-Albumin-Binding Gemcitabine Prodrugs Promote Bioavailability and Tumor Accumulation

Zhang, Huicong, Wang, Kuanglei, Na, Kexin, Li, Dan, Li, Zhenbao, Zhao, Dongyang, Zhong, Lu, Wang, Menglin, Kou, Longfa, Luo, Cong, Zhang, Haotian, Kan, Qiming, Ding, Huaiwei, He, Zhonggui, Sun, Jin

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 4.75 MB

english, 2018

24

Synergistic breast tumor cell killing achieved by intracellular co-delivery of doxorubicin and disulfiram via core–shell–corona nanoparticles

Tao, Xiaoguang, Gou, Jingxin, Zhang, Qianying, Tan, Xinyi, Ren, Tianyang, Yao, Qing, Tian, Bin, Kou, Longfa, Zhang, Ling, Tang, Xing

Journal:

Biomaterials Science

Year:

2018

Language:

english

File:

PDF, 3.54 MB

english, 2018

25

Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy

Du, Yuqian, Tian, Chutong, Wang, Menglin, Huang, Di, Wei, Wei, Liu, Yan, Li, Lin, Sun, Bingjun, Kou, Longfa, Kan, Qiming, Liu, Kexin, Luo, Cong, Sun, Jin, He, Zhonggui

Journal:

Year:

2018

Language:

english

File:

PDF, 1.85 MB

english, 2018

26

Development of a Supercritical Fluid Chromatography-Tandem Mass Spectrometry Method for the Determination of Azacitidine in Rat Plasma and Its Application to a Bioavailability Study

Li, Dongpo, Zhang, Tianhong, Kou, Longfa, Zhang, Youxi, Sun, Jin, He, Zhonggui

Journal:

Year:

2013

Language:

english

File:

PDF, 480 KB

english, 2013

27

Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types

Kou, Longfa, Bhutia, Yangzom D., Yao, Qing, He, Zhonggui, Sun, Jin, Ganapathy, Vadivel

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 2.85 MB

english, 2018

28

In situ low-immunogenic albumin-conjugating- corona guiding nanoparticles for tumor-targeting chemotherapy

Li, Zhenbao, Li, Dan, Li, Qingsong, Luo, Cong, Li, Jing, Kou, Longfa, Zhang, Dong, Zhang, Haotian, Zhao, Songyan, Kan, Qiming, Liu, Jie, Zhang, Peng, Liu, Xiaohong, Sun, Yinghua, Wang, Yongjun, He, Zh

Journal:

Biomaterials Science

Year:

2018

Language:

english

File:

PDF, 4.25 MB

english, 2018

29

Emerging advances in P-glycoprotein inhibitory nanomaterials for drug delivery

Kou, Longfa, Sun, Rui, Bhutia, Yangzom D., Yao, Qing, Chen, Ruijie

Journal:

Expert Opinion on Drug Delivery

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

30

Tumor-targeted drug delivery and sensitization by MMP2-responsive polymeric micelles

Yao, Qing, Liu, Yin, Kou, Longfa, Tu, Ying, Tang, Xing, Zhu, Lin

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2019

Language:

english

File:

PDF, 2.78 MB

english, 2019

31

Tumor-targeted drug delivery and sensitization by MMP2-responsive polymeric micelles

Yao, Qing, Liu, Yin, Kou, Longfa, Tu, Ying, Tang, Xing, Zhu, Lin

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2019

File:

PDF, 2.78 MB

2019

32

An Ambidextrous Approach to Disrupt Redox Balance in Tumor Cell with Increased ROS Production and Decreased GSH Synthesis for Cancer Therapy

Kou, Longfa, Sun, Rui, Xiao, Shuyi, Zheng, Yawen, Chen, Zhiwei, Cai, Aimin, Zheng, Hailun, Yao, Qing, Ganapathy, Vadivel, Chen, Ruijie

Journal:

ACS Applied Materials & Interfaces

Year:

2019

Language:

english

File:

PDF, 1.80 MB

english, 2019

33

Recent development and biomedical applications of decellularized extracellular matrix biomaterials

Yao, Qing, Zheng, Ya-Wen, Lan, Qing-Hua, Kou, Longfa, Xu, He-Lin, Zhao, Ying-Zheng

Journal:

Materials Science and Engineering: C

Year:

2019

Language:

english

File:

PDF, 1.38 MB

english, 2019

34

Recent development and biomedical applications of decellularized extracellular matrix biomaterials

Yao, Qing, Zheng, Ya-Wen, Lan, Qing-Hua, Kou, Longfa, Xu, He-Lin, Zhao, Ying-Zheng

Journal:

Materials Science and Engineering: C

Year:

2019

File:

PDF, 1.38 MB

2019

35

In vitro and in vivo evaluation of didymin cyclodextrin inclusion complexes: characterization and chemosensitization activity

Yao, Qing, Lin, Meng-Ting, Lan, Qing-Hua, Huang, Zhi-Wei, Zheng, Ya-Wen, Jiang, Xue, Zhu, Yin-Di, Kou, Longfa, Xu, He-Lin, Zhao, Ying-Zheng

Journal:

Year:

2020

Language:

english

File:

PDF, 3.40 MB

english, 2020

36

Exploiting crosslinked decellularized matrix to achieve uterus regeneration and construction

Yao, Qing, Zheng, Ya-Wen, Lin, Hui-Long, Lan, Qing-Hua, Huang, Zhi-Wei, Wang, Li-Fen, Chen, Rui, Xiao, Jian, Kou, Longfa, Xu, He-Lin, Zhao, Ying-Zheng

Journal:

Artificial Cells, Nanomedicine, and Biotechnology

Year:

2020

Language:

english

File:

PDF, 2.56 MB

english, 2020

37

Therapeutic options and drug delivery strategies for the prevention of intrauterine adhesions

Kou, Longfa, Jiang, Xue, Xiao, Shuyi, Zhao, Ying-Zheng, Yao, Qing, Chen, Ruijie

Journal:

Journal of Controlled Release

Year:

2020

File:

PDF, 6.73 MB

2020

38

In vitro and in vivo evaluation of didymin cyclodextrin inclusion complexes: characterization and chemosensitization activity

Yao, Qing, Lin, Meng-Ting, Lan, Qing-Hua, Huang, Zhi-Wei, Zheng, Ya-Wen, Jiang, Xue, Zhu, Yin-Di, Kou, Longfa, Xu, He-Lin, Zhao, Ying-Zheng

Journal:

Year:

2020

File:

PDF, 3.40 MB

2020

39

Exploiting crosslinked decellularized matrix to achieve uterus regeneration and construction

Yao, Qing, Zheng, Ya-Wen, Lin, Hui-Long, Lan, Qing-Hua, Huang, Zhi-Wei, Wang, Li-Fen, Chen, Rui, Xiao, Jian, Kou, Longfa, Xu, He-Lin, Zhao, Ying-Zheng

Journal:

Artificial Cells, Nanomedicine, and Biotechnology

Year:

2020

File:

PDF, 2.56 MB

2020

40

Bilirubin Improves the Quality and Function of Hypothermic Preserved Islets by Its Antioxidative and Anti-inflammatory Effect

Yao, Qing, Jiang, Xue, Huang, Zhi-Wei, Lan, Qing-Hua, Wang, Li-Fen, Chen, Rui, Li, Xin-Ze, Kou, Longfa, Xu, He-Lin, Zhao, Ying-Zheng

Journal:

Transplantation Journal

Year:

2019

File:

PDF, 1.08 MB

2019

41

Localized controlled release of bilirubin from β-cyclodextrin conjugated ε-polylysine to attenuate oxidative stress and inflammation in transplanted islets

Yao, Qing, Huang, Zhi-Wei, Zhai, Yuan-Yuan, Yue, Meng, Luo, Lan-Zi, Xue, Peng-Peng, Han, Yong-Hui, Xu, He-Lin, Kou, Longfa, Zhao, Ying-Zheng

Journal:

ACS Applied Materials & Interfaces

Year:

2020

File:

PDF, 2.03 MB

2020

42

Protective effects and mechanisms of bilirubin nanomedicine against acute pancreatitis

Yao, Qing, Jiang, Xue, Zhai, Yuan-Yuan, Luo, Lan-Zi, Xu, He-Lin, Xiao, Jian, Kou, Longfa, Zhao, Ying-Zheng

Journal:

Journal of Controlled Release

Year:

2020

File:

PDF, 5.06 MB

2020

43

The role of transporters in cancer redox homeostasis and cross-talk with nanomedicines

Kou, Longfa, Jiang, Xinyu, Huang, Huirong, Lin, Xinlu, Zhang, Youting, Yao, Qing, Chen, Ruijie

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 2.50 MB

2020

44

Special topic: Emerging role of transporters in drug interaction and delivery

Kou, Longfa, He, Zhonggui, Sun, Jin

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 298 KB

2020

45

Carbidopa suppresses prostate cancer via aryl hydrocarbon receptor-mediated ubiquitination and degradation of androgen receptor

Chen, Zhiwei, Cai, Aimin, Zheng, Hailun, Huang, Huirong, Sun, Rui, Cui, Xiao, Ye, Weijian, Yao, Qing, Chen, Ruijie, Kou, Longfa

Journal:

Year:

2020

File:

PDF, 3.08 MB

2020

46

Tumor microenvironment-responsive multistaged liposome induces apoptosis and ferroptosis by amplifying oxidative stress for enhanced cancer therapy

Kou, Longfa, Sun, Rui, Jiang, Xinyu, Lin, Xinlu, Huang, Huirong, Bao, Shihui, Zhang, Youting, Li, Chao, Chen, Ruijie, Yao, Qing

Journal:

ACS Applied Materials & Interfaces

Year:

2020

File:

PDF, 1.97 MB

2020

47

Bilirubin Protects Transplanted Islets by Targeting Ferroptosis

Yao, Qing, Sun, Rui, Bao, Shihui, Chen, Ruijie, Kou, Longfa

Journal:

Frontiers in Pharmacology

Year:

2020

File:

PDF, 3.63 MB

2020

48

Silk fibroin-modified disulfiram/zinc oxide nanocomposites for pH triggered release of Zn2+ and synergistic antitumor efficacy

Zhao, Ying-Zheng, Lin, Meng-Ting, Lan, Qing-Hua, Zhai, Yuan-Yuan, Xu, He-Lin, Xiao, Jian, Kou, Longfa, Yao, Qing

Journal:

Molecular Pharmaceutics

Year:

2020

File:

PDF, 2.17 MB

2020

49

Therapeutic application and construction of bilirubin incorporated nanoparticles

Yao, Qing, Chen, Ruijie, Ganapathy, Vadivel, Kou, Longfa

Journal:

Journal of Controlled Release

Year:

2020

File:

PDF, 7.17 MB

2020

50

Transporter-Targeted Nano-Sized Vehicles for Enhanced and Site-Specific Drug Delivery

Kou, Longfa, Yao, Qing, Zhang, Hailin, Chu, Maoping, Bhutia, Yangzom D., Chen, Ruijie, Ganapathy, Vadivel

Journal:

Year:

2020

File:

PDF, 2.58 MB

2020

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